KMID : 0362919850030020113
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Journal of the Korean Society for Therapeutic Radiology and Oncology 1985 Volume.3 No. 2 p.113 ~ p.121
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Radiotherapy Results of the Non-Hodgkin¢¥s Lymphoma in the Head and Neckt
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Kim Jung-Soo
Kim Il-Han Ha Sung-Whan Park Charn-Il SUh Eun-Hee Ahn Geung-Hwan Bang Young-Jue Kim Noe-Kyeong
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Abstract
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This is a retrospecitve analysis of 54 patients with stage ¥° or ¥± Non-Hodgkin¢¥s lymphoma involving the head and neck region treated with curative radiotherapy in the Department of Therapeutic Radiology, Seoul National University Hospital during the period of February 1979 through September 1982.
The minimum follow-up period was 24 months.
The review of histologic slides was available in 36 cases. Waldeyer¢¥s ring was the most common extranodal sites (46%).
41% of patients were in the stage ¥° and 59% in the stage ¥± by Ann Arbor classification. Of the 44 patients who responded after radiotherapy, 24 patients (54.5%) subsequently relapsed. Regional recurrence rate was 29%, distant metastasis was 54% and simultaneous regional recurrence and distant metastasis was 17%.
The survival rate and disease free survival at 2 years were 57% and 45% respectively. Those patients with a large primary lesion (over 6cm in diameter), multiple conglomerated. extranodal site and diffuse cell type, experienced a high rate of distant metastasis. Therefore it seems desirable to study the use of adjuvant chemotherapy in those patients with a high probability of distant metastasis.
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KEYWORD
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Non-Hodgkin¢¥s lymphoma, Head and neck region, Radiotherapy, Prognostic factors
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